| Event | 1 | X | 2 | Prediction | Score |
| Rapid 1923 vs Voluntari ROM2021/09/24 – 18:00 | 2.05 | 3.05 | 3.80 | YES | ? – ? |
| Coventry vs Peterborough ECH2021/09/24 – 19:45 | 1.75 | 3.70 | 4.75 | YES | ? – ? |
| West Bromwich vs QPR ECH2021/09/24 – 20:00 | 1.70 | 3.80 | 4.50 | YES | ? – ? |
| Gornik Leczna vs Lechia Gdansk POL2021/09/24 – 17:00 | 3.55 | 3.30 | 2.05 | YES | ? – ? |
| Jagiellonia Bialystok vs Lech Poznan POL2021/09/24 – 19:30 | 4.00 | 3.65 | 1.83 | YES | ? – ? |
| Jahn Regensburg vs Erzgebirge Aue GER 22021/09/24 – 17:30 | 1.70 | 3.80 | 4.75 | YES | ? – ? |
| ADO Den Haag vs Roda NET EER2021/09/24 – 19:00 | 2.45 | 3.70 | 2.45 | YES | ? – ? |
| Altay Izmir vs Besiktas TUR2021/09/24 – 18:00 | 5.00 | 3.85 | 1.65 | YES | ? – ? |
| Al-Ittihad Jeddah vs Al Taawon SAUDI2021/09/24 – 18:25 | 1.43 | 4.75 | 6.20 | YES | ? – ? |
| Arbroath vs Kilmarnock SCO CHAMP2021/09/24 – 19:45 | 3.55 | 3.35 | 2.00 | YES | ? – ? |
| Barrow vs Newport ENG L22021/09/24 – 19:45 | 2.35 | 3.10 | 2.95 | YES | ? – ? |
